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In vitro culture of freshly isolated Trypanosoma brucei brucei bloodstream forms results in gene copy-number changes

Most researchers who study unicellular eukaryotes work with an extremely limited number of laboratory-adapted isolates that were obtained from the field decades ago, but the effects of passage in laboratory rodents, and adaptation to in vitro culture, have been little studied. For example, the vast...

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Detalles Bibliográficos
Autores principales: Mulindwa, Julius, Ssentamu, Geofrey, Matovu, Enock, Kamanyi Marucha, Kevin, Aresta-Branco, Francisco, Helbig, Claudia, Clayton, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459984/
https://www.ncbi.nlm.nih.gov/pubmed/34516555
http://dx.doi.org/10.1371/journal.pntd.0009738