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In vitro culture of freshly isolated Trypanosoma brucei brucei bloodstream forms results in gene copy-number changes
Most researchers who study unicellular eukaryotes work with an extremely limited number of laboratory-adapted isolates that were obtained from the field decades ago, but the effects of passage in laboratory rodents, and adaptation to in vitro culture, have been little studied. For example, the vast...
Autores principales: | Mulindwa, Julius, Ssentamu, Geofrey, Matovu, Enock, Kamanyi Marucha, Kevin, Aresta-Branco, Francisco, Helbig, Claudia, Clayton, Christine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459984/ https://www.ncbi.nlm.nih.gov/pubmed/34516555 http://dx.doi.org/10.1371/journal.pntd.0009738 |
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