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TGF-β inhibitor RepSox suppresses osteosarcoma via the JNK/Smad3 signaling pathway

Osteosarcoma (OS) is the most common malignant bone tumor and the long-term survival rates remain unsatisfactory. Transforming growth factor-β (TGF-β) has been revealed to play a crucial role in OS progression, and RepSox is an effective TGF-β inhibitor. In the present study, the effect of RepSox on...

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Detalles Bibliográficos
Autores principales: He, Dengwei, Gao, Jiawei, Zheng, Lin, Liu, Shijie, Ye, Lin, Lai, Hehuan, Pan, Bin, Pan, Wenzheng, Lou, Chao, Chen, Zhenzhong, Fan, Shunwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460063/
https://www.ncbi.nlm.nih.gov/pubmed/34533199
http://dx.doi.org/10.3892/ijo.2021.5264