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TGF-β inhibitor RepSox suppresses osteosarcoma via the JNK/Smad3 signaling pathway
Osteosarcoma (OS) is the most common malignant bone tumor and the long-term survival rates remain unsatisfactory. Transforming growth factor-β (TGF-β) has been revealed to play a crucial role in OS progression, and RepSox is an effective TGF-β inhibitor. In the present study, the effect of RepSox on...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460063/ https://www.ncbi.nlm.nih.gov/pubmed/34533199 http://dx.doi.org/10.3892/ijo.2021.5264 |