The distinct role of the four voltage sensors of the skeletal Ca(V)1.1 channel in voltage-dependent activation

Initiation of skeletal muscle contraction is triggered by rapid activation of RYR1 channels in response to sarcolemmal depolarization. RYR1 is intracellular and has no voltage-sensing structures, but it is coupled with the voltage-sensing apparatus of Ca(V)1.1 channels to inherit voltage sensitivity...

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Detalles Bibliográficos
Autores principales: Savalli, Nicoletta, Angelini, Marina, Steccanella, Federica, Wier, Julian, Wu, Fenfen, Quinonez, Marbella, DiFranco, Marino, Neely, Alan, Cannon, Stephen C., Olcese, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460119/
https://www.ncbi.nlm.nih.gov/pubmed/34546289
http://dx.doi.org/10.1085/jgp.202112915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460119/
https://www.ncbi.nlm.nih.gov/pubmed/34546289
http://dx.doi.org/10.1085/jgp.202112915

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