NHR-8 and P-glycoproteins uncouple xenobiotic resistance from longevity in chemosensory C. elegans mutants

Longevity is often associated with stress resistance, but whether they are causally linked is incompletely understood. Here we investigate chemosensory-defective Caenorhabditis elegans mutants that are long-lived and stress resistant. We find that mutants in the intraflagellar transport protein gene...

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Detalles Bibliográficos
Autores principales: Guerrero, Gabriel A, Derisbourg, Maxime J, Mayr, Felix AMC, Wester, Laura E, Giorda, Marco, Dinort, J Eike, Hartman, Matías D, Schilling, Klara, Alonso-De Gennaro, María José, Lu, Ryan J, Benayoun, Bérénice A, Denzel, Martin S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460253/
https://www.ncbi.nlm.nih.gov/pubmed/34448454
http://dx.doi.org/10.7554/eLife.53174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460253/
https://www.ncbi.nlm.nih.gov/pubmed/34448454
http://dx.doi.org/10.7554/eLife.53174

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