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Witnessing the structural evolution of an RNA enzyme

An RNA polymerase ribozyme that has been the subject of extensive directed evolution efforts has attained the ability to synthesize complex functional RNAs, including a full-length copy of its own evolutionary ancestor. During the course of evolution, the catalytic core of the ribozyme has undergone...

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Detalles Bibliográficos
Autores principales: Portillo, Xavier, Huang, Yu-Ting, Breaker, Ronald R, Horning, David P, Joyce, Gerald F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460264/
https://www.ncbi.nlm.nih.gov/pubmed/34498588
http://dx.doi.org/10.7554/eLife.71557