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Witnessing the structural evolution of an RNA enzyme
An RNA polymerase ribozyme that has been the subject of extensive directed evolution efforts has attained the ability to synthesize complex functional RNAs, including a full-length copy of its own evolutionary ancestor. During the course of evolution, the catalytic core of the ribozyme has undergone...
Autores principales: | Portillo, Xavier, Huang, Yu-Ting, Breaker, Ronald R, Horning, David P, Joyce, Gerald F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460264/ https://www.ncbi.nlm.nih.gov/pubmed/34498588 http://dx.doi.org/10.7554/eLife.71557 |
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