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Role of Matrix Metalloproteinases in Myelin Abnormalities and Mechanical Allodynia in Rodents with Diabetic Neuropathy

The treatment of diabetic neuropathic pain (DNP) is a major clinical challenge. The underlying mechanisms of diabetic neuropathy remain unclear, and treatment approaches are limited. Here, we report that the gelatinases MMP-9 and MMP-2 play a critical role in axonal demyelination and DNP in rodents....

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Detalles Bibliográficos
Autores principales: Deng, Xueting, Ma, Pingchuan, Wu, Mingzheng, Liao, Huabao, Song, Xue-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460301/
https://www.ncbi.nlm.nih.gov/pubmed/34631222
http://dx.doi.org/10.14336/AD.2021.0126