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Targeting Mitochondrial Network Disorganization is Protective in C. elegans Models of Huntington’s Disease

Huntington’s disease (HD) is an adult-onset neurodegenerative disease caused by a trinucleotide CAG repeat expansion in the HTT gene. While the pathogenesis of HD is incompletely understood, mitochondrial dysfunction is thought to be a key contributor. In this work, we used C. elegans models to eluc...

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Detalles Bibliográficos
Autores principales:	Machiela, Emily, Rudich, Paige D, Traa, Annika, Anglas, Ulrich, Soo, Sonja K, Senchuk, Megan M, Van Raamsdonk, Jeremy M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	JKL International LLC 2021
Materias:	Orginal Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460302/ https://www.ncbi.nlm.nih.gov/pubmed/34631219 http://dx.doi.org/10.14336/AD.2021.0404

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