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Tongxinluo Exerts Inhibitory Effects on Pyroptosis and Amyloid-β Peptide Accumulation after Cerebral Ischemia/Reperfusion in Rats

Amyloid-β peptide (Aβ) accumulation is a detrimental factor in cerebral ischemia/reperfusion (I/R) injuries accounting for dementia induced by ischemic stroke. In addition to blood brain barrier (BBB), the glymphatic system mediated by aquaporin-4 (AQP-4) on astrocytic endfeet functions as an import...

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Detalles Bibliográficos
Autores principales: Wang, Bing, Lyu, Zhongkuan, Chan, Yuanjin, Li, Qiyue, Zhang, Li, Liu, Kaili, Li, Yaming, Yu, Zhonghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460392/
https://www.ncbi.nlm.nih.gov/pubmed/34567216
http://dx.doi.org/10.1155/2021/5788602