Azidothymidine Downregulates Insulin-Like Growth Factor-1 Induced Lipogenesis by Suppressing Mitochondrial Biogenesis and Mitophagy in Immortalized Human Sebocytes

BACKGROUND: Increased sebum secretion is considered the main causative factor in the pathogenesis of acne. There is an unmet pharmacological need for a novel drug that can control sebum production with a favorable adverse effect profile. OBJECTIVE: To investigate the effect of azidothymidine on lipi...

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Detalles Bibliográficos
Autores principales: Yoo, Jin Gwi, Li, Xue Mei, Lee, Jae Kyung, Park, Sanghyun, Hong, Dongkyun, Jung, Kyung Eun, Lee, Young, Seo, Young-Joon, Kim, Chang Deok, Shin, Jung-Min, Choi, Chong Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Dermatological Association; The Korean Society for Investigative Dermatology 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460479/
https://www.ncbi.nlm.nih.gov/pubmed/34616123
http://dx.doi.org/10.5021/ad.2021.33.5.425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460479/
https://www.ncbi.nlm.nih.gov/pubmed/34616123
http://dx.doi.org/10.5021/ad.2021.33.5.425

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