Imitating evolution’s tinkering by protein engineering reveals extension of human galectin-7 activity

Wild-type lectins have distinct types of modular design. As a step to explain the physiological importance of their special status, hypothesis-driven protein engineering is used to generate variants. Concerning adhesion/growth-regulatory galectins, non-covalently associated homodimers are commonly e...

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Detalles Bibliográficos
Autores principales: Ludwig, Anna-Kristin, Michalak, Malwina, Gabba, Adele, Kutzner, Tanja J., Beckwith, Donella M., FitzGerald, Forrest G., García Caballero, Gabriel, Manning, Joachim C., Kriegsmann, Mark, Kaltner, Herbert, Murphy, Paul V., Cudic, Maré, Kopitz, Jürgen, Gabius, Hans-Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460509/
https://www.ncbi.nlm.nih.gov/pubmed/34152508
http://dx.doi.org/10.1007/s00418-021-02004-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460509/
https://www.ncbi.nlm.nih.gov/pubmed/34152508
http://dx.doi.org/10.1007/s00418-021-02004-w

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