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Novel serotonin 5-HT(2A) receptor antagonists derived from 4-phenylcyclohexane-5-spiro-and 5-methyl-5-phenyl-hydantoin, for use as potential antiplatelet agents

BACKGROUND: Antiplatelet drugs have been used in the treatment of acute coronary syndromes and for the prevention of recurrent events. Unfortunately, many patients remain resistant to the available antiplatelet treatment. Therefore, there is a clinical need to synthesize novel antiplatelet agents, w...

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Detalles Bibliográficos
Autores principales: Czopek, Anna, Kubacka, Monika, Bucki, Adam, Siwek, Agata, Filipek, Barbara, Pawłowski, Maciej, Kołaczkowski, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460535/
https://www.ncbi.nlm.nih.gov/pubmed/34115343
http://dx.doi.org/10.1007/s43440-021-00284-6