Antidepressant-like effect of dehydrozingerone from Zingiber officinale by elevating monoamines in brain: in silico and in vivo studies

BACKGROUND: Dehydrozingerone (DHZ) is an active ingredient of Zingiber officinale and structural half analogue of curcumin. In the present study, DHZ was evaluated for monoamine oxidase (MAO) inhibitory activity in silico and antidepressant activity in vivo. METHOD: The binding affinity of DHZ with...

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Detalles Bibliográficos
Autores principales: Moorkoth, Sudheer, Prathyusha, N. Sai, Manandhar, Suman, Xue, Yuanxin, Sankhe, Runali, Pai, K. S. R., Kumar, Nitesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460585/
https://www.ncbi.nlm.nih.gov/pubmed/34181212
http://dx.doi.org/10.1007/s43440-021-00252-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460585/
https://www.ncbi.nlm.nih.gov/pubmed/34181212
http://dx.doi.org/10.1007/s43440-021-00252-0

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