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Antidepressant-like effect of dehydrozingerone from Zingiber officinale by elevating monoamines in brain: in silico and in vivo studies
BACKGROUND: Dehydrozingerone (DHZ) is an active ingredient of Zingiber officinale and structural half analogue of curcumin. In the present study, DHZ was evaluated for monoamine oxidase (MAO) inhibitory activity in silico and antidepressant activity in vivo. METHOD: The binding affinity of DHZ with...
Autores principales: | Moorkoth, Sudheer, Prathyusha, N. Sai, Manandhar, Suman, Xue, Yuanxin, Sankhe, Runali, Pai, K. S. R., Kumar, Nitesh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460585/ https://www.ncbi.nlm.nih.gov/pubmed/34181212 http://dx.doi.org/10.1007/s43440-021-00252-0 |
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