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CroS(R391), an ortholog of the λ Cro repressor, plays a major role in suppressing polV(R391)‐dependent mutagenesis

When subcloned into low‐copy‐number expression vectors, rumAB, encoding polV(R391) (RumA′(2)B), is best characterized as a potent mutator giving rise to high levels of spontaneous mutagenesis in vivo. This is in dramatic contrast to the poorly mutable phenotype when polV(R391) is expressed from the...

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Detalles Bibliográficos
Autores principales: McDonald, John P., Quiros, Dominic R., Vaisman, Alexandra, Mendez, Antonio R., Reyelt, Jan, Schmidt, Marlen, Gonzalez, Martín, Woodgate, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460599/
https://www.ncbi.nlm.nih.gov/pubmed/34184328
http://dx.doi.org/10.1111/mmi.14777