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Revealing Escherichia coli type II l-asparaginase active site flexible loop in its open, ligand-free conformation

Since 1993, when the structure of Escherichia coli type II l-asparaginase (EcAII) in complex with l-aspartate was firstly reported, many structures of the wild type and mutated enzyme have been deposited in the Protein Data Bank. None of them report the full structure of the monomer in its ligand-fr...

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Detalles Bibliográficos
Autores principales: Maggi, Maristella, Meli, Massimiliano, Colombo, Giorgio, Scotti, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460627/
https://www.ncbi.nlm.nih.gov/pubmed/34556749
http://dx.doi.org/10.1038/s41598-021-98455-1