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Revealing Escherichia coli type II l-asparaginase active site flexible loop in its open, ligand-free conformation
Since 1993, when the structure of Escherichia coli type II l-asparaginase (EcAII) in complex with l-aspartate was firstly reported, many structures of the wild type and mutated enzyme have been deposited in the Protein Data Bank. None of them report the full structure of the monomer in its ligand-fr...
Autores principales: | Maggi, Maristella, Meli, Massimiliano, Colombo, Giorgio, Scotti, Claudia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460627/ https://www.ncbi.nlm.nih.gov/pubmed/34556749 http://dx.doi.org/10.1038/s41598-021-98455-1 |
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