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Polygenic risk for obsessive-compulsive disorder (OCD) predicts brain response during working memory task in OCD, unaffected relatives, and healthy controls

Alterations in frontal and parietal neural activations during working memory task performance have been suggested as a candidate endophenotype of obsessive-compulsive disorder (OCD) in studies involving first-degree relatives. However, the direct link between genetic risk for OCD and neuro-functiona...

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Detalles Bibliográficos
Autores principales: Heinzel, Stephan, Kaufmann, Christian, Grützmann, Rosa, Klawohn, Julia, Riesel, Anja, Bey, Katharina, Heilmann-Heimbach, Stefanie, Weinhold, Leonie, Ramirez, Alfredo, Wagner, Michael, Kathmann, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460640/
https://www.ncbi.nlm.nih.gov/pubmed/34556731
http://dx.doi.org/10.1038/s41598-021-98333-w