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Role of pyruvate in maintaining cell viability and energy production under high-glucose conditions

Pyruvate functions as a key molecule in energy production and as an antioxidant. The efficacy of pyruvate supplementation in diabetic retinopathy and nephropathy has been shown in animal models; however, its significance in the functional maintenance of neurons and Schwann cells under diabetic condi...

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Detalles Bibliográficos
Autores principales: Yako, Hideji, Niimi, Naoko, Kato, Ayako, Takaku, Shizuka, Tatsumi, Yasuaki, Nishito, Yasumasa, Kato, Koichi, Sango, Kazunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460646/
https://www.ncbi.nlm.nih.gov/pubmed/34556698
http://dx.doi.org/10.1038/s41598-021-98082-w