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MCM9 is associated with germline predisposition to early-onset cancer—clinical evidence

Mutated MCM9 has been associated with primary ovarian insufficiency. Although MCM9 plays a role in genome maintenance and has been reported as a candidate gene in a few patients with inherited colorectal cancer (CRC), it has not been clearly established as a cancer predisposition gene. We re-evaluat...

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Detalles Bibliográficos
Autores principales: Goldberg, Yael, Aleme, Ola, Peled-Perets, Lilach, Castellvi-Bel, Sergi, Nielsen, Maartje, Shalev, Stavit A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460657/
https://www.ncbi.nlm.nih.gov/pubmed/34556653
http://dx.doi.org/10.1038/s41525-021-00242-4