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SAP130 released by damaged tubule drives necroinflammation via miRNA-219c/Mincle signaling in acute kidney injury

Tubules injury and immune cell activation are the common pathogenic mechanisms in acute kidney injury (AKI). However, the exact modes of immune cell activation following tubule damage are not fully understood. Here we uncovered that the release of cytoplasmic spliceosome associated protein 130 (SAP1...

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Detalles Bibliográficos
Autores principales: Lv, Lin-Li, Wang, Cui, Li, Zuo-Lin, Cao, Jing-Yuan, Zhong, Xin, Feng, Ye, Chen, Jun, Tang, Tao-Tao, Ni, Hai-Feng, Wu, Qiu-Li, Wang, Bin, Lan, Hui-Yao, Liu, Bi-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460660/
https://www.ncbi.nlm.nih.gov/pubmed/34556635
http://dx.doi.org/10.1038/s41419-021-04131-7