Serglycin induces osteoclastogenesis and promotes tumor growth in giant cell tumor of bone

Giant cell tumor of bone (GCTB) is an aggressive osteolytic bone tumor characterized by the within-tumor presence of osteoclast-like multinucleated giant cells (MGCs), which are induced by the neoplastic stromal cells and lead to extensive bone destruction. However, the underlying mechanism of the p...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Yunfei, Cheng, Dongdong, Lian, Cheng, Liu, Yingjie, Luo, Wenqian, Wang, Yuan, Ma, Chengxin, Wu, Qiuyao, Tian, Pu, He, Dasa, Jia, Zhenchang, Lv, Xianzhe, Zhang, Xue, Pan, Zhen, Lu, Jinxi, Xiao, Yansen, Zhang, Peiyuan, Liang, Yajun, Yang, Qingcheng, Hu, Guohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460728/
https://www.ncbi.nlm.nih.gov/pubmed/34556636
http://dx.doi.org/10.1038/s41419-021-04161-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460728/
https://www.ncbi.nlm.nih.gov/pubmed/34556636
http://dx.doi.org/10.1038/s41419-021-04161-1

Ejemplares similares