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Reconstructing and counting genomic fragments through tagmentation-based haploid phasing

Single-cell sequencing provides a new level of granularity in studying the heterogeneous nature of cancer cells. For some cancers, this heterogeneity is the result of copy number changes of genes within the cellular genomes. The ability to accurately determine such copy number changes is critical in...

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Detalles Bibliográficos
Autores principales: Leong, Patrick P. T., Mihajlović, Aleksandar, Bogdanović, Nadežda, Breberina, Luka, Xi, Larry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460729/
https://www.ncbi.nlm.nih.gov/pubmed/34556684
http://dx.doi.org/10.1038/s41598-021-97852-w