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Reconstructing and counting genomic fragments through tagmentation-based haploid phasing
Single-cell sequencing provides a new level of granularity in studying the heterogeneous nature of cancer cells. For some cancers, this heterogeneity is the result of copy number changes of genes within the cellular genomes. The ability to accurately determine such copy number changes is critical in...
Autores principales: | Leong, Patrick P. T., Mihajlović, Aleksandar, Bogdanović, Nadežda, Breberina, Luka, Xi, Larry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460729/ https://www.ncbi.nlm.nih.gov/pubmed/34556684 http://dx.doi.org/10.1038/s41598-021-97852-w |
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