Berberine is an insulin secretagogue targeting the KCNH6 potassium channel

Coptis chinensis is an ancient Chinese herb treating diabetes in China for thousands of years. However, its underlying mechanism remains poorly understood. Here, we report the effects of its main active component, berberine (BBR), on stimulating insulin secretion. In mice with hyperglycemia induced...

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Detalles Bibliográficos
Autores principales: Zhao, Miao-Miao, Lu, Jing, Li, Sen, Wang, Hao, Cao, Xi, Li, Qi, Shi, Ting-Ting, Matsunaga, Kohichi, Chen, Chen, Huang, Haixia, Izumi, Tetsuro, Yang, Jin-Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460738/
https://www.ncbi.nlm.nih.gov/pubmed/34556670
http://dx.doi.org/10.1038/s41467-021-25952-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460738/
https://www.ncbi.nlm.nih.gov/pubmed/34556670
http://dx.doi.org/10.1038/s41467-021-25952-2

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