High CYP27A1 expression is a biomarker of favorable prognosis in premenopausal patients with estrogen receptor positive primary breast cancer

27-hydroxycholesterol (27HC), synthesized from cholesterol by the enzyme CYP27A1, differentially impacts estrogen receptor positive (ER+) breast cancer (BC) cell growth depending on estrogen levels. This study examined the association between CYP27A1 expression and prognosis in a cohort of 193 preme...

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Detalles Bibliográficos
Autores principales: Inasu, Maria, Bendahl, Pär-Ola, Fernö, Mårten, Malmström, Per, Borgquist, Signe, Kimbung, Siker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460751/
https://www.ncbi.nlm.nih.gov/pubmed/34556659
http://dx.doi.org/10.1038/s41523-021-00333-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460751/
https://www.ncbi.nlm.nih.gov/pubmed/34556659
http://dx.doi.org/10.1038/s41523-021-00333-6

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