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High CYP27A1 expression is a biomarker of favorable prognosis in premenopausal patients with estrogen receptor positive primary breast cancer

27-hydroxycholesterol (27HC), synthesized from cholesterol by the enzyme CYP27A1, differentially impacts estrogen receptor positive (ER+) breast cancer (BC) cell growth depending on estrogen levels. This study examined the association between CYP27A1 expression and prognosis in a cohort of 193 preme...

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Detalles Bibliográficos
Autores principales:	Inasu, Maria, Bendahl, Pär-Ola, Fernö, Mårten, Malmström, Per, Borgquist, Signe, Kimbung, Siker
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460751/ https://www.ncbi.nlm.nih.gov/pubmed/34556659 http://dx.doi.org/10.1038/s41523-021-00333-6

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