Fibroblast growth factor 21 (FGF21) alleviates senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the SIRT1-mTOR signaling pathway

Osteoarthritis (OA) is a complex condition that involves both apoptosis and senescence and currently cannot be cured. Fibroblast growth factor 21 (FGF21), known for its role as a potent regulator of glucose and energy metabolism, protects from various diseases, possibly by mediating autophagy. In th...

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Detalles Bibliográficos
Autores principales: Lu, Hongwei, Jia, Chao, Wu, Dengying, Jin, Haidong, Lin, Zeng, Pan, Jun, Li, Xiucui, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460788/
https://www.ncbi.nlm.nih.gov/pubmed/34556628
http://dx.doi.org/10.1038/s41419-021-04157-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460788/
https://www.ncbi.nlm.nih.gov/pubmed/34556628
http://dx.doi.org/10.1038/s41419-021-04157-x

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