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Fibroblast growth factor 21 (FGF21) alleviates senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the SIRT1-mTOR signaling pathway

Osteoarthritis (OA) is a complex condition that involves both apoptosis and senescence and currently cannot be cured. Fibroblast growth factor 21 (FGF21), known for its role as a potent regulator of glucose and energy metabolism, protects from various diseases, possibly by mediating autophagy. In th...

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Detalles Bibliográficos
Autores principales:	Lu, Hongwei, Jia, Chao, Wu, Dengying, Jin, Haidong, Lin, Zeng, Pan, Jun, Li, Xiucui, Wang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460788/ https://www.ncbi.nlm.nih.gov/pubmed/34556628 http://dx.doi.org/10.1038/s41419-021-04157-x

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