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Microglial-expressed genetic risk variants, cognitive function and brain volume in patients with schizophrenia and healthy controls

Changes in immune function are associated with variance in cognitive functioning in schizophrenia. Given that microglia are the primary innate immune cells in the brain, we examined whether schizophrenia risk-associated microglial genes (measured via polygenic score analysis) explained variation in...

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Detalles Bibliográficos
Autores principales: Corley, Emma, Holleran, Laurena, Fahey, Laura, Corvin, Aiden, Morris, Derek W., Donohoe, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460789/
https://www.ncbi.nlm.nih.gov/pubmed/34556640
http://dx.doi.org/10.1038/s41398-021-01616-z