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Hypoxia inducible factor signaling in breast tumors controls spontaneous tumor dissemination in a site-specific manner

Hypoxia is a common feature in tumors and induces signaling that promotes tumor cell survival, invasion, and metastasis, but the impact of hypoxia inducible factor (HIF) signaling in the primary tumor on dissemination to bone in particular remains unclear. To better understand the contributions of h...

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Detalles Bibliográficos
Autores principales: Todd, Vera M., Vecchi, Lawrence A., Clements, Miranda E., Snow, Katherine P., Ontko, Cayla D., Himmel, Lauren, Pinelli, Christopher, Rafat, Marjan, Johnson, Rachelle W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460839/
https://www.ncbi.nlm.nih.gov/pubmed/34556788
http://dx.doi.org/10.1038/s42003-021-02648-3