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Podocyte Foot Process Effacement Precedes Albuminuria and Glomerular Hypertrophy in CD2-Associated Protein Deficient Mice

Background: Podocyte foot process effacement is a key histologic finding in proteinuric kidney disease. We previously showed that 3-week old CD2AP-deficient mice have significant proteinuria, glomerular hypertrophy and mesangial expansion. The goal of this study is to use morphometry to establish th...

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Detalles Bibliográficos
Autores principales: Basgen, John M., Wong, Jenny S., Ray, Justina, Nicholas, Susanne B., Campbell, Kirk N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460869/
https://www.ncbi.nlm.nih.gov/pubmed/34568396
http://dx.doi.org/10.3389/fmed.2021.745319