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The Potential and Limitations of Precision Oncology: Lessons Learned from Whole-Exome Sequencing in an Exceptional Response to Everolimus in Advanced Renal Cell Carcinoma

Through elucidating the genetic mechanisms of drug sensitivity, precision medicine aims to improve patient selection and response to therapy. Exceptional responders are patients that exhibit exquisite and durable responses to targeted therapy, providing a rare opportunity to identify the molecular b...

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Detalles Bibliográficos
Autores principales: Pilling, Amanda, Wee, Christopher, Bar-Meir, Eliezer, Dyson, Gregory, Hwang, Ok, Gupta, Nilesh, Chitale, Dhananjay, Hwang, Clara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460888/
https://www.ncbi.nlm.nih.gov/pubmed/34703436
http://dx.doi.org/10.1159/000516277