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The Potential and Limitations of Precision Oncology: Lessons Learned from Whole-Exome Sequencing in an Exceptional Response to Everolimus in Advanced Renal Cell Carcinoma
Through elucidating the genetic mechanisms of drug sensitivity, precision medicine aims to improve patient selection and response to therapy. Exceptional responders are patients that exhibit exquisite and durable responses to targeted therapy, providing a rare opportunity to identify the molecular b...
Autores principales: | Pilling, Amanda, Wee, Christopher, Bar-Meir, Eliezer, Dyson, Gregory, Hwang, Ok, Gupta, Nilesh, Chitale, Dhananjay, Hwang, Clara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460888/ https://www.ncbi.nlm.nih.gov/pubmed/34703436 http://dx.doi.org/10.1159/000516277 |
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