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Mechanotransduction Regulates Reprogramming Enhancement in Adherent 3D Keratocyte Cultures
Suspended spheroid culture using ultralow attachment plates (ULAPs) is reported to effect corneal fibroblast reprogramming. Polydimethylsiloxane (PDMS), with hydrophobic and soft substrate properties, facilitates adherent spheroid formation that promotes cellular physical reprogramming into stem-lik...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460903/ https://www.ncbi.nlm.nih.gov/pubmed/34568299 http://dx.doi.org/10.3389/fbioe.2021.709488 |