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Mechanotransduction Regulates Reprogramming Enhancement in Adherent 3D Keratocyte Cultures

Suspended spheroid culture using ultralow attachment plates (ULAPs) is reported to effect corneal fibroblast reprogramming. Polydimethylsiloxane (PDMS), with hydrophobic and soft substrate properties, facilitates adherent spheroid formation that promotes cellular physical reprogramming into stem-lik...

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Detalles Bibliográficos
Autores principales:	Li, Shenyang, Ding, Chengcheng, Guo, Yonglong, Zhang, Yanan, Wang, Hao, Sun, Xihao, Zhang, Jun, Cui, Zekai, Chen, Jiansu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460903/ https://www.ncbi.nlm.nih.gov/pubmed/34568299 http://dx.doi.org/10.3389/fbioe.2021.709488

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