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Mechanotransduction Regulates Reprogramming Enhancement in Adherent 3D Keratocyte Cultures

Suspended spheroid culture using ultralow attachment plates (ULAPs) is reported to effect corneal fibroblast reprogramming. Polydimethylsiloxane (PDMS), with hydrophobic and soft substrate properties, facilitates adherent spheroid formation that promotes cellular physical reprogramming into stem-lik...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Li, Shenyang, Ding, Chengcheng, Guo, Yonglong, Zhang, Yanan, Wang, Hao, Sun, Xihao, Zhang, Jun, Cui, Zekai, Chen, Jiansu
التنسيق: Online مقال نص
اللغة:English
منشور في: Frontiers Media S.A. 2021
الموضوعات:
الوصول للمادة أونلاين:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460903/
https://www.ncbi.nlm.nih.gov/pubmed/34568299
http://dx.doi.org/10.3389/fbioe.2021.709488