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Mechanotransduction Regulates Reprogramming Enhancement in Adherent 3D Keratocyte Cultures

Suspended spheroid culture using ultralow attachment plates (ULAPs) is reported to effect corneal fibroblast reprogramming. Polydimethylsiloxane (PDMS), with hydrophobic and soft substrate properties, facilitates adherent spheroid formation that promotes cellular physical reprogramming into stem-lik...

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Príomhchruthaitheoirí: Li, Shenyang, Ding, Chengcheng, Guo, Yonglong, Zhang, Yanan, Wang, Hao, Sun, Xihao, Zhang, Jun, Cui, Zekai, Chen, Jiansu
Formáid: Online Alt Téacs
Teanga:English
Foilsithe / Cruthaithe: Frontiers Media S.A. 2021
Ábhair:
Rochtain ar líne:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460903/
https://www.ncbi.nlm.nih.gov/pubmed/34568299
http://dx.doi.org/10.3389/fbioe.2021.709488