Mechanotransduction Regulates Reprogramming Enhancement in Adherent 3D Keratocyte Cultures

Suspended spheroid culture using ultralow attachment plates (ULAPs) is reported to effect corneal fibroblast reprogramming. Polydimethylsiloxane (PDMS), with hydrophobic and soft substrate properties, facilitates adherent spheroid formation that promotes cellular physical reprogramming into stem-lik...

Description complète

Détails bibliographiques
Auteurs principaux: Li, Shenyang, Ding, Chengcheng, Guo, Yonglong, Zhang, Yanan, Wang, Hao, Sun, Xihao, Zhang, Jun, Cui, Zekai, Chen, Jiansu
Format: Online Article Texte
Langue:English
Publié: Frontiers Media S.A. 2021
Sujets:
Bioengineering and Biotechnology
Accès en ligne:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460903/
https://www.ncbi.nlm.nih.gov/pubmed/34568299
http://dx.doi.org/10.3389/fbioe.2021.709488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460903/
https://www.ncbi.nlm.nih.gov/pubmed/34568299
http://dx.doi.org/10.3389/fbioe.2021.709488

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