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In silico Identification of Key Factors Driving the Response of Muscle Sensory Neurons to Noxious Stimuli

Nociceptive nerve endings embedded in muscle tissue transduce peripheral noxious stimuli into an electrical signal [i.e., an action potential (AP)] to initiate pain sensations. A major contributor to nociception from the muscles is mechanosensation. However, due to the heterogeneity in the expressio...

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Detalles Bibliográficos
Autores principales: Nagaraja, Sridevi, Queme, Luis F., Hofmann, Megan C., Tewari, Shivendra G., Jankowski, Michael P., Reifman, Jaques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461020/
https://www.ncbi.nlm.nih.gov/pubmed/34566566
http://dx.doi.org/10.3389/fnins.2021.719735