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Complement Alternative and Mannose-Binding Lectin Pathway Activation Is Associated With COVID-19 Mortality

BACKGROUND: The SARS-CoV-2 infection triggers excessive immune response resulting in increased levels of pro-inflammatory cytokines, endothelial injury, and intravascular coagulopathy. The complement system (CS) activation participates to this hyperinflammatory response. However, it is still unclear...

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Detalles Bibliográficos
Autores principales: Defendi, Federica, Leroy, Corentin, Epaulard, Olivier, Clavarino, Giovanna, Vilotitch, Antoine, Le Marechal, Marion, Jacob, Marie-Christine, Raskovalova, Tatiana, Pernollet, Martine, Le Gouellec, Audrey, Bosson, Jean-Luc, Poignard, Pascal, Roustit, Matthieu, Thielens, Nicole, Dumestre-Pérard, Chantal, Cesbron, Jean-Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461024/
https://www.ncbi.nlm.nih.gov/pubmed/34567008
http://dx.doi.org/10.3389/fimmu.2021.742446