The short-term effects of ORKAMBI (lumacaftor/ivacaftor) on regional and distal lung structures using functional respiratory imaging

BACKGROUND: Lumacaftor/ivacaftor (LUM/IVA) has shown modest benefits in previous research, but the exact effects in the cystic fibrosis (CF) lung remain unclear. This study aims to offer novel information on the mode of action of the cystic fibrosis transmembrane conductance regulator (CFTR)-modulat...

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Detalles Bibliográficos
Autores principales: Lauwers, Eline, Belmans, Dennis, Mignot, Benjamin, Ides, Kris, Van Hoorenbeeck, Kim, Snoeckx, Annemiek, Van Holsbeke, Cedric, Nowé, Vicky, Van Braeckel, Eva, De Backer, Wilfried, De Backer, Jan, Verhulst, Stijn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461124/
https://www.ncbi.nlm.nih.gov/pubmed/34541955
http://dx.doi.org/10.1177/17534666211046774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461124/
https://www.ncbi.nlm.nih.gov/pubmed/34541955
http://dx.doi.org/10.1177/17534666211046774

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