Cetuximab–siRNA Conjugate Linked Through Cationized Gelatin Knocks Down KRAS G12C Mutation in NSCLC Sensitizing the Cells Toward Gefitinib

Delivery of small-interfering RNA (siRNA) has been of great interest in the past decade for effective gene silencing. To overcome synthetic and regulatory challenges posed by nanoparticle-mediated siRNA delivery, antibody–siRNA conjugate (ARC) platform is emerging as a potential siRNA delivery syste...

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Detalles Bibliográficos
Autores principales: Sreedurgalakshmi, K., Srikar, R., Harikrishnan, K., Srinivasan, Lakshmi, Rajkumari, Reena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461128/
https://www.ncbi.nlm.nih.gov/pubmed/34542333
http://dx.doi.org/10.1177/15330338211041453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461128/
https://www.ncbi.nlm.nih.gov/pubmed/34542333
http://dx.doi.org/10.1177/15330338211041453

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