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Cetuximab–siRNA Conjugate Linked Through Cationized Gelatin Knocks Down KRAS G12C Mutation in NSCLC Sensitizing the Cells Toward Gefitinib
Delivery of small-interfering RNA (siRNA) has been of great interest in the past decade for effective gene silencing. To overcome synthetic and regulatory challenges posed by nanoparticle-mediated siRNA delivery, antibody–siRNA conjugate (ARC) platform is emerging as a potential siRNA delivery syste...
Autores principales: | Sreedurgalakshmi, K., Srikar, R., Harikrishnan, K., Srinivasan, Lakshmi, Rajkumari, Reena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461128/ https://www.ncbi.nlm.nih.gov/pubmed/34542333 http://dx.doi.org/10.1177/15330338211041453 |
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