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Age at Disease Onset Associates With Oxidative Stress, Neuroinflammation, and Impaired Synaptic Plasticity in Relapsing-Remitting Multiple Sclerosis

Age at onset is the main risk factor for disease progression in patients with relapsing-remitting multiple sclerosis (RR-MS). In this cross-sectional study, we explored whether older age is associated with specific disease features involved in the progression independent of relapse activity (PIRA)....

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Detalles Bibliográficos
Autores principales: Stampanoni Bassi, Mario, Gilio, Luana, Iezzi, Ennio, Moscatelli, Alessandro, Pekmezovic, Tatjana, Drulovic, Jelena, Furlan, Roberto, Finardi, Annamaria, Mandolesi, Georgia, Musella, Alessandra, Galifi, Giovanni, Fantozzi, Roberta, Bellantonio, Paolo, Storto, Marianna, Centonze, Diego, Buttari, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461180/
https://www.ncbi.nlm.nih.gov/pubmed/34566620
http://dx.doi.org/10.3389/fnagi.2021.694651