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Salubrinal Regulates the Apoptosis of Adrenocortical Carcinoma Cells via the PERK/eIF2α/ATF4 Signaling Pathway

The protein-kinase-R- (PKR-) like endoplasmic reticulum kinase (PERK) signaling pathway is a well-known promoter of cell apoptosis. In this study, we aimed to determine whether salubrinal (Sal), a selective activator of eukaryotic translation initiation factor 2 (eIF2α), can induce apoptosis of huma...

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Detalles Bibliográficos
Autores principales: Wu, Lili, Liang, Chunfeng, Huang, Xuemei, Deng, Xiujun, Jiang, Jiming, Luo, Zuojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461226/
https://www.ncbi.nlm.nih.gov/pubmed/34567111
http://dx.doi.org/10.1155/2021/5038130