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The Curious Anti-Pathology of the Wld(s) Mutation: Paradoxical Postsynaptic Spine Growth Accompanies Delayed Presynaptic Wallerian Degeneration

The Wld(s) mutation, which arose spontaneously in C57Bl/6 mice, remarkably delays the onset of Wallerian degeneration of axons. This remarkable phenotype has transformed our understanding of mechanisms contributing to survival vs. degeneration of mammalian axons after separation from their cell bodi...

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Detalles Bibliográficos
Autores principales: Steward, Oswald, Yonan, Jennifer M., Falk, Paula M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461245/
https://www.ncbi.nlm.nih.gov/pubmed/34566580
http://dx.doi.org/10.3389/fnmol.2021.735919