Cargando…
The Curious Anti-Pathology of the Wld(s) Mutation: Paradoxical Postsynaptic Spine Growth Accompanies Delayed Presynaptic Wallerian Degeneration
The Wld(s) mutation, which arose spontaneously in C57Bl/6 mice, remarkably delays the onset of Wallerian degeneration of axons. This remarkable phenotype has transformed our understanding of mechanisms contributing to survival vs. degeneration of mammalian axons after separation from their cell bodi...
Autores principales: | Steward, Oswald, Yonan, Jennifer M., Falk, Paula M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461245/ https://www.ncbi.nlm.nih.gov/pubmed/34566580 http://dx.doi.org/10.3389/fnmol.2021.735919 |
Ejemplares similares
-
The progressive nature of Wallerian degeneration in wild-type and slow Wallerian degeneration (Wld(S)) nerves
por: Beirowski, Bogdan, et al.
Publicado: (2005) -
Expression of the neuroprotective slow Wallerian degeneration (Wld(S)) gene in non-neuronal tissues
por: Wishart, Thomas M, et al.
Publicado: (2009) -
Protective role of Wallerian degeneration slow (Wld(s)) gene against retinal ganglion cell body damage in a Wallerian degeneration model
por: WANG, CHENG-HU, et al.
Publicado: (2013) -
Wld(S) requires Nmnat1 enzymatic activity and N16–VCP interactions to suppress Wallerian degeneration
por: Avery, Michelle A., et al.
Publicado: (2009) -
Modified cell cycle status in a mouse model of altered neuronal vulnerability (slow Wallerian degeneration; Wld(s))
por: Wishart, Thomas M, et al.
Publicado: (2008)