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Dnj1 Promotes Virulence in Cryptococcus neoformans by Maintaining Robust Endoplasmic Reticulum Homeostasis Under Temperature Stress

The capacity of opportunistic fungal pathogens such as Cryptococcus neoformans to cause disease is dependent on their ability to overcome an onslaught of stresses including elevated temperature under mammalian host conditions. Protein chaperones and co-chaperones play key roles in thermotolerance. I...

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Detalles Bibliográficos
Autores principales: Horianopoulos, Linda C., Lee, Christopher W. J., Hu, Guanggan, Caza, Mélissa, Kronstad, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461255/
https://www.ncbi.nlm.nih.gov/pubmed/34566931
http://dx.doi.org/10.3389/fmicb.2021.727039